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Slideshow of Neurodegeneration

The Neurodegeneration network described in A Systems Approach to Prion Disease is shown below as a slide show. The experimental design for this study is explained in the Prion Mouse Model. Relative changes of the transcripts for the corresponding proteins are represented in color changes: red-upregulation, green-downregulation, yellow-no change. Data for the transcriptional changes are from BL6 mice infected with RML prions, at 14 weeks, 16 weeks, 18 weeks, 20 weeks, and 22 weeks after inoculation. The slide show displays the network at these particular timepoints. See Supplementary Figure S5 for additional details.

Click here to see all five timepoints in a new window.

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