The table produced by the Gene Dossier contains the following columns:
The number indicates the number of prion-specific publications associated
with the gene. Clicking on the magnifying glass opens a pop-up window with
the prion-specific publications.
Expression Rank in Human Brain:
A number indicates that the gene is expressed in human whole brain tissue as determined by data in the BioGPS (formerly the Novartis GNF SymAtlas database). This number represents a rank within an experiment. Clicking on the
rank takes you to the entry in the Tissue Expression tool.
Allen Mouse Brain Atlas:
A tick indicates that the mouse ortholog of the gene has an entry in the Allen Mouse Brain Atlas. Clicking on the tick takes you to the entry in the Allen Mouse Brain Atlas.
Found in Human Plasma:
A tick indicates that the gene has an entry in the Plasma Peptide Atlas
which means that the protein product of the gene has been robustly
detected by mass spectroscopy in human serum or plasma. Clicking on the
tick takes you to the entry in the Plasma Peptide Atlas.
To sort the results, click on any column heading. For example, to sort by Found in Plasma, click on this heading. Sorting can be done in
ascending or descending order.
The table has "drag-and-drop" columns. To change the column order, click on the
column header and drag it to another position. For example, to place the
Found in Plasma column next to the Gene Name column, click on Found in Plasma
and move the column next to the Gene Name column.
If a gene identifier matches multiple genes, a box will be displayed on the results page saying "There were ambiguous terms in your query. Click here to resolve them." You can click the link to correct the identifier. To pick the correct identifier(s), click on the box next to the appropriate identifier(s) and click on Submit Corrections. A new results page with the correct identifier(s) will be shown.
You can add a gene to the results by entering a gene identifier in the "Add a new
gene box" and clicking Go.
You can save the displayed genes by clicking the "save list to My PDDB" link
at the top of the page. You can use the genes in another PDDB program by
clicking the "send list to tool" link at the top of the page. Clicking on one of
the tools will cause a new page to be loaded with the gene list already included
in the "Select a PDDB List".